Dont take LSD unless you are very well prepared, unless you are specif — LSD

"The underground press was convinced that I was a junkie, an acid head. … But I dont do drugs. I dont like being fucked up. Ive got enough bizarre chemicals floating around in my head. Im just naturally like this."

"Rationale for Treatment with LSD and UML Our interest in these drugs was due in part to their psychotomimetic effect, hoping thereby that the autistic defenses of schizophrenic children might be broken down. Of equal interest, on a theoretical basis, is the serotonin inhibiting effect and of greater interest is their effect on the autonomic and central nervous system. Brodie has described the effects of LSD and other hallucinogenic agents as "arousal and increased responsiveness to sensory stimuli, preponderance of sympathetic activity and increased skeletal muscle tone and activity." Of particular interest is their tonic effect on the vascular bed especially of the brain, as has been shown with UML in vascular headaches. The known effects of these drugs on perception further increases their interest in the treatment of schizophrenia. Such drugs were of interest to us for the treatment of childhood schizophrenia since our definition of this condition is a disorder in maturation characterized by an embryonic primitive plasticity in all areas of integrative brain functioning from which behavior subsequently arises. This includes all autonomic functions, perception, emotion, intelligence. It was hoped that these drugs might prove some-what specific in modifying the basic process as well as the secondary symptoms. Autism is seen as a withdrawal or denial defense against disturbing sensations arising from disturbed autonomic function and perceptual function and anxiety in the young child with lagging and atypical maturation. It was hoped that this autism might be disrupted and that more normal autonomic functions in the vascular bed, brain, intestines, skin and other organs as well as in perception would permit more normal development."

"It’s a psychic energizer… It releases the subconscious. It makes you see all your guilts, fears, repressions and insecurities. It makes you free."

"I believe that shortly after LSD was discovered, it was recognized as being of great value to psychoanalysis and psychiatry. It was not considered to be an escape. It was a very important discovery at that time, and for fifteen years it could be used legally in psychiatric treatment and for scientific study in humans. During this time, Delysid, the name I gave to LSD, was used safely, and was the subject of thousands of publications in the professional literature. … This early work was very well documented, and shows how well research with LSD went until it became part of the drug scene in the 1960s. So, from originally being part of the therapeutic pharmacopeia, LSD became a drug of the street and inevitably it was made illegal. Because of this reputation, it became unavailable to the medical field, and so the research, which had been very open, was stopped. Now it appears that this research may start again. The importance of such investigations appears to be recognized by the health authorities, and so it is my hope that finally the prohibition is coming to an end, and the medical field can return to the explorations which were forced to stop thirty years ago."

"I took some bad acid in November of 1965, and the after effect left me crazy and helpless for six months. My mind would drift into a place that was very electrical and crackly, filled with harsh, abrasive, low grade, cartoony, tawdry carnival visions. There was a nightmarish mechanical aspect to everyday life. My ego was so shattered, so fragmented that it didnt get in the way during what was the most unself-conscious period of my life. I was kind of on automatic pilot and was still constantly drawing. Most of my popular characters—Mr. Natural, Flaky Foont, Angelfood McSpade, Eggs Ackley, The Snoid, The Vulture Demonesses, Av n Gar, Shuman the Human, the Truckin guys, Devil Girl—all suddenly appeared in the drawings in my sketchbook in this period, early 1966. Amazing! I was relieved when it was finally over, but I also immediately missed the egoless state of that strange interlude. LSD put me somewhere else. I wasnt sure where. All I know is, it was a strange place. Psychedelic drugs broke me out of my social programming. It was a good thing for me, traumatic though, and I may have been permanently damaged by the whole thing, Im not sure. I see LSD as a positive, important life experience for me, but I certainly wouldnt recommend it to anyone else."

"Deliberate provocation of mystical experience, particularly by LSD and related hallucinogens, in contrast to spontaneous visionary experiences, entails dangers that must not be underestimated. Practitioners must take into account the peculiar effects of these substances, namely their ability to influence our consciousness, the innermost essence of our being. The history of LSD to date amply demonstrates the catastrophic consequences that can ensue when its profound effect is misjudged and the substance is mistaken for a pleasure drug. Special internal and external advance preparations are required; with them, an LSD experiment can become a meaningful experience. Wrong and inappropriate use has caused LSD to become my problem child."