One important idea is that science is a means whereby learning is achi — George E. P. Box

"Statistical criteria should (1) be sensitive to change in the specific factors tested, (2) be insensitive to changes, of a magnitude likely to occur in practice, in extraneous factors."

"Essentially, all models are wrong, but some are useful."

"Since all models are wrong the scientist cannot obtain a "correct" one by excessive elaboration. On the contrary following William of Occam he should seek an economical description of natural phenomena. Just as the ability to devise simple but evocative models is the signature of the great scientist so overelaboration and overparameterization is often the mark of mediocrity."

"We have a large reservoir of engineers (and scientists) with a vast background of engineering know how. They need to learn statistical methods that can tap into the knowledge. Statistics used as a catalyst to engineering creation will, I believe, always result in the fastest and most economical progress…"

"The researcher hoping to break new ground in the theory of experimental design should involve himself in the design of actual experiments. The investigator who hopes to revolutionize decision theory should observe and take part in the making of important decisions."

"All models are wrong; some models are useful."