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We conclude — unexpectedly — that there is little evidence for the neo — Mutant

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"We conclude — unexpectedly — that there is little evidence for the neo-Darwinian view: its theoretical foundations and the experimental evidence supporting it are weak, and there is no doubt that mutations of large effect are sometimes important in adaptation. We hasten to add, however, that we are not "macromutationists" who believe that adaptations are nearly always based on major genes. The neo-Darwinian view could well be correct. … We hope to encourage evolutionists to reexamine this neglected question and to provide evidence to settle it."
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Mutant
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In biology, and especially in genetics, a mutant is an organism or a new genetic character arising or resulting from an instance of mutation, which is generally an alteration of the DNA sequence of the genome or chromosome of an organism. It is a characteristic that would not be observed naturally in a specimen. The term mutant is also applied to a virus with an alteration in its nucleotide sequen

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"According to Goldschmidt, all that evolution by the usual mutations—dubbed "micromutations"—can accomplish is to bring about "diversification strictly within species, usually, if not exclusively, for the sake of adaptation of the species to specific conditions within the area which it is able to occupy." New species, genera, and higher groups arise at once, by cataclysmic saltations—termed macromutations or systematic mutations—which bring about in one step a basic reconstruction of the whole organism. The role of natural selection in this process becomes "reduced to the simple alternative: immediate acceptance or rejection." A new form of life having been thus catapulted into being, the details of its structures and functions are subsequently adjusted by micromutation and selection. It is unnecessary to stress here that this theory virtually rejects evolution as this term is usually understood (to evolve means to unfold or to develop gradually), and that the systematic mutations it postulates have never been observed. It is possible to imagine a mutation so drastic that its product becomes a monster hurling itself beyond the confines of species, genus, family, or class. But in what Goldschmidt has called the "hopeful monster" the harmonious system, which any organism must necessarily possess, must be transformed at once into a radically different, but still sufficiently coherent, system to enable the monster to survive. The assumption that such a prodigy may, however rarely, walk the earth overtaxes ones credulity, even though it may be right that the existence of life in the cosmos is in itself an extremely improbable event."
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"The X-Men, created by Jewish American comics legends Stan Lee and Jack Kirby in 1963, is a team of mutants, a class of human being first introduced as people that “possess an extrapower…one which ordinary humans do not!!” (EUX1 #1: 8ii). Especially after the introduction of the mutant-hunting robot Sentinels in X-Men #14 (Nov. 1965, EUX1), Marvel Comics’ mutants have been increasingly inscribed with allegorical Otherness. They have been subject to many of the prejudices that have historically plagued marginalized minorities, including, among other things, forced and voluntary segregation, slurs, persecution, and genocidal campaigns, and, conspiracy theories about their aims as a group."
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"Last night I encountered a dream cat with a very long neck and a body like a human fetus, gray and transluscent. I dont know what it needs or how to provide for it. Another dream years ago of a human child with eyes on stalks. It is very small, but can walk and talk "Dont you want me?" Again, I dont know how to care for the child. But I am dedicated to protecting and nurturing him at any cost! It is the function of the Guardian to protect hybrids and mutants in the vulnerable stage of infancy."
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