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When one body combines with another in more than one proportion, the s — John Dalton

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"When one body combines with another in more than one proportion, the second proportion appears to be some multiple or divisor of the first; and this circumstance, observed and ingeniously illustrated by Mr. Dalton, led him to adopt the atomic hypothesis of chemical changes, which had been ably defended by Mr. Higgins in 1789, namely, that the chemical elements consist of certain indestructible particles which unite one and one, or one and two, or in some definite [] numbers."
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John Dalton
John Dalton
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John Dalton was an English chemist, physicist, and meteorologist whose work laid the foundations of modern atomic theory and stoichiometric chemistry. Building on earlier ideas about the indivisibility of matter and his own precise measurements of combining ratios, Dalton proposed that each chemical element consists of identical atoms of characteristic weight, and that compounds are formed when at

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"Chemical analysis and synthesis go no farther than to the separation of particles one from another, and to their reunion. No new creation or destruction of matter is within the reach of chemical agency. We might as well attempt to introduce a new planet into the solar system, or to annihilate one already in existence, as to create or destroy a particle of hydrogen. All the changes we can produce, consist in separating particles that are in a state of cohesion or combination, and joining those that were previously at a distance."
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John Dalton
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"He has shewn to us how vividly he formed these ideas, that they were no mere fancies which had passed through his brain, but distinct impressions, ready prepared for utterance. No doubt is left upon our minds as to his opinions, which are, that every piece of matter, even the smallest, must follow the laws of the largest; that when pounds of matter unite, the atoms contained in them must unite also, until we come to the fact that only atoms can really be said to unite. Now as the conception of any fraction of an atom is a contradiction and impossible, they must constantly unite as wholes, and the proportion will be constant. If constant in the smallest quantities, then so in the largest, explaining the permanency of the constitution of bodies so much disputed, and making it a law of nature. If two compound bodies unite, the same law is followed out."
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John Dalton