Now nuns have blended into everybody else or else faded away. Vocation — John Updike

"Suspect each moment, for it is a thief, tiptoeing away with more than it brings."

"[Janice] Looking back from this distance, she cant think any more that Harry was all to blame for their early troubles, he had just been trying life on too: life and sex and making babies and finding out who you are."

"Writing criticism is to writing fiction and poetry as hugging the shore is to sailing in the open sea."

"That a marriage ends is less than ideal; but all things end under heaven, and if temporality is held to be invalidating, then nothing real succeeds."

"I would rather have as my patron a host of anonymous citizens digging into their own pockets for the price of a book or a magazine than a small body of enlightened and responsible men administering public funds. I would rather chance my personal vision of truth striking home here and there in the chaos of publication that exists than attempt to filter it through a few sets of official, honorably public-spirited scruples."

"Each morning my characters greet me with misty faces willing, though chilled, to muster for another days progress through the dazzling quicksand the marsh of blank paper."

"Be the change that you wish to see in the world."

"we are engaged in a grim experiment never before attempted. We are subjecting whole populations to exposure to chemicals which animal experiments have proved to be extremely poisonous and in many cases cumulative in their effect. These exposures now begin at or before birth and-unless we change our methods-will continue through the lifetime of those now living. No one knows what the result will be, because we have no previous experience to guide us."

"pity this busy monster, manunkind, not. Progress is a comfortable disease: your victim (death and life safely beyond) plays with the bigness of his littleness"

"I believe that the unity of man as opposed to other living things derives from the fact that man is the conscious life of himself. Man is conscious of himself, of his future, which is death, of his smallness, of his impotence; he is aware of others as others; man is in nature, subject to its laws even if he transcends it with his thought."

"“We need brains, is the bottom line,” Ivy said. “We’re not hunter-gatherers anymore. We’re all living like patients in the intensive care unit of a hospital. What keeps us alive isn’t bravery, or athleticism, or any of those other skills that were valuable in a caveman society. It’s our ability to master complex technological skills. It is our ability to be nerds. We need to breed nerds.”"

"I have been clinically depressed for most of my life. I once used drugs to fix it. Then I stopped. I stopped because I decided they were making me stupid, and Id rather be miserable than stupid. I am what I am."